Management in Oncological Prevention on the Example of Selenium Supplementation (Se) Cover Image

Zarządzanie w profilaktyce onkologicznej na przykładzie suplementacji selenem (Se)
Management in Oncological Prevention on the Example of Selenium Supplementation (Se)

Author(s): Krzysztof Sieja, Katarzyna Sygit, Marian Sygit, Agnieszka Genowska
Subject(s): Management and complex organizations, Health and medicine and law, Family and social welfare
Published by: Społeczna Akademia Nauk
Keywords: selenium (Se); prophylaxis; genital cancers in women; prostate cancer; management of oncological prophylaxis;

Summary/Abstract: Genital cancers in women and prostate cancer are among the most common malignant tumors occurring in Poland. To reduce the risk of developing the above-mentioned neoplasms need proper management of prophylaxis, in which the use of selenium may be an important item. Numerous studies conducted for many years in Poland and at dawn have demonstrated the significant effect of selenium in the prevention of cancer – including genital cancers in women and prostate cancer. The aim of this work is to indicate the influence of selenium (Se) on cancer prevention as an important element in the prevention of female genital cancer and prostate cancer. So far, the largest epidemiological studies on the relationship between serum selenium and subsequent cancer development have proved that low serum selenium levels may increase the risk of certain cancers in men and women, especially genital cancers. Numerous studies conducted on a group of women and men showed that the threshold value of serum selenium concentration is associated with an increased risk of cancer - is <85μg / l (p = 0.019, OR-2.7). Epidemiological studies carried out in various countries, and above all in the Scandinavian countries and the United States, showed a negative correlation between the amount of selenium consumed and the incidence of cancer in humans. It has also been shown to reduce the concentration of this micronutrient in the blood of patients with oncological diseases in comparison with the values obtained in healthy people. The results of numerous national and international prospective studies indicate that low selenium intake and or serum/plasma nails concentration is a high risk marker for the majority of cancers, including genital cancers in women and prostate tumors; is an important element in the management of preventive oncology activities.

  • Issue Year: 18/2017
  • Issue No: 10.3
  • Page Range: 203-212
  • Page Count: 10
  • Language: Polish