Niedobory witaminy D a konsekwencje zdrowotne
The health consequences of vitamin D deficiency

Summary/Abstract: Vitamin D (calcitriol) plays a significant role in many processes. Obtained from diet or synthesized in the skin under UV radiation, it is used not only in calcium homeostasis, but also beneficially affects systems such as the muscoskeletal, immune, and cardiovascular. In recent years, a lot of research have been done regarding the influence of Vitamin D on the human organism and, more importantly, it has been revealed that Vitamin D deficiency is the most common avitaminosis. It is assumed, that about one million people have Vitamin D deficiency globally. Calcitriol deficitis manifested in children by abnormal bone mass and impaired bone mineralization, leading to numerous deformities of the skeleton and in adults by osteopenia. It has been observed that the risk of cancers such as breast, ovarian, prostate, lung, esophagus and pancreas increases proportionally depending on the distance from the equator, as reduced exposure to sunlight limits the ability to produce this vitamin. Studies show a clear dependence of vitamin D deficiency and increased risk of diseases such as type 2 diabetes, cardiovascular diseases, frequent infections of the upper respiratory tract, cognitive disorders, mental disorders, allergies and autoimmune diseases.

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