Phytochemical and in Vitro Antioxidant Studies of Primula Veris (L.) Growing Wild in Kosovo
Phytochemical and in Vitro Antioxidant Studies of Primula Veris (L.) Growing Wild in Kosovo

Summary/Abstract: The antioxidant capacities, total phenolic and flavonoid content of five different extracts (Et2O, CHCl3, EtOAc, n-BuOH and H2O) of Primula veris (L.) growing wild in Kosovo were analyzed. Total phenolic and flavonoid content were quantitatively determined to the Primula veris (L.) growing wild in North-Western part of Kosovo in two different altitude levels (670 m and 1200 m). The amount of total phenolics in Primula veris (L.) extracts ranged from 5.10 mg GAE/g d.e. in altitude 1200 m to 17.30 mg GAE/g d.e. in altitude 670 m. The amount of total flavonoids in Primula veris (L.) extracts ranged from 12.15 mg RE/g d.e. in altitude 670 m to 31.43 mg GAE/g d.e. in altitude 1200 m. Free radical scavenging capacity (RSC) was evaluated by measuring the scavenging capacity of extracts on DPPH, NO as well as on hydrogen peroxide (H2O2). EtOAc, n-BuOH and H2O extracts of Primula veris (L.) expressed very strong scavenger activity. On the other hand, Et2O and CHCl3 extracts showed much weaker effect in the neutralization of DPPH, NO and H2O2. The observed differences in antioxidant activity could be partially explained by the levels of phenolics and flavonoids in extracts of Primula veris (L.). Hence, this plant can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals.

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