Ketamine – drug and substance of abuse Cover Image

Ketamin – léčivo a zneužívaná látka
Ketamine – drug and substance of abuse

Author(s): Stanislav Rádl
Subject(s): Public Administration, Clinical psychology, Criminology, Health and medicine and law
Published by: Národní protidrogová centrála SKPV PČR
Keywords: ketamine; esketamine; anesthetic; antidepressant; abuse potential;

Summary/Abstract: The article summarizes historical facts regarding the dissociative anesthetic ketamine from its discovery, introduction into practice in human and veterinary medicine to its off-label use for the treatment of depression. It also discusses its abuse as a recreational drug with dissociative and euphoric effects. Finally, the potential of abuse of the recently introduced intranasal formulation of the pure S-enantiomer is also discussed (Spravato®).

  • Issue Year: 32/2026
  • Issue No: 1
  • Page Range: 4-11
  • Page Count: 8
  • Language: Czech
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