QUALITY OF LIFE OF PATIENTS WITH TYPE 2 DIABETES MELLITUS
QUALITY OF LIFE OF PATIENTS WITH TYPE 2 DIABETES MELLITUS

Summary/Abstract: Type 2 diabetes mellitus is a chronic metabolic disease whose prevalence continues to increase, making it one of the leading public health challenges of the modern era. It is characterized by insulin resistance and progressive metabolic dysregulation, resulting in chronic hyperglycemia. Due to its long-term nature and the need for daily self-management, the disease significantly affects the physical, psychological, social, and functional aspects of patients’ lives. Consequently, contemporary therapeutic approaches have gradually shifted from an exclusive focus on glycemic control toward a more holistic model that includes the assessment and improvement of patients’ quality of life. Aim: To provide an overview of current evidence on the determinants of quality of life in individuals with type 2 diabetes mellitus, emphasizing the role of health literacy, psychological factors, sociodemographic characteristics, and diabetes-related clinical complications. Methods: This paper is based on a narrative review of the available scientific literature. Relevant studies were identified through searches of electronic databases (PubMed, Scopus, Web of Science, and Google Scholar) following the PRISMA guidelines. Studies examining health-related quality of life (HRQoL) among adults with type 2 diabetes mellitus were considered eligible. A total of eight original research articles published in 2024 were included in the final analysis. Results: The reviewed studies indicate that most patients perceive their quality of life as moderate. A strong positive association is identified between health literacy and quality of life, with higher levels of health literacy contributing to better self-care and adherence to therapeutic recommendations, which emerged as the strongest predictors of a good quality of life. Conversely, psychological factors such as depression, anxiety, and diabetes distress, as well as clinical factors including disease duration, insulin therapy, and microvascular and macrovascular complications (e.g., peripheral neuropathy and heart failure), were found to significantly impair daily functioning and reduce the quality of life. Furthermore, older age, lower educational attainment, and poorer socioeconomic status were associated with less favorable outcomes. Quality of life among individuals with type 2 diabetes mellitus is a complex construct influenced by the interaction of clinical, psychological, and behavioral determinants. Improving the quality of life requires a multidisciplinary approach that extends beyond pharmacological treatment alone. The integration of structured health literacy programs, continuous self-management education, psychological support, and the strengthening of social support networks represents an essential strategy for reducing emotional burden, improving disease management, and enhancing overall well-being and the quality of life in the long term.

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