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Aspects of Social Support in the Case of Abstinent Alcoholic

Author(s): Iános-Mátyás-Tamás Mihók-Géczi / Language(s): English Issue: 2/2015

Abstinence is an indispensable premise in the case of alcohol addicts. In maintaining this, aside for a solid motivation and the task to alter his behavior and attitude towards life, an essential role is played by the element of Social Support. Understanding, as an individual, the way in which the Social Support system to which he belongs functions, is determined in offering a protective or, contrary to that, obnoxious role, with the feeling of abandonment, loneliness or alienation. The present study is an element of a future sociologic research focused on alcohol addicts, now abstinent. The batch of participants was made up of 116 persons, men with ages between 26 and 73 years (with an average age of 47.55 years), abstinent alcoholics with a minimum of three months since their debut or their last relapse. Utilizing the Multidimensional Scale of Perceived Social Support / MSPSS (Zimet and colab. 1988), the perception of an abstinent alcoholic about the grade of fitness of the social support has been evaluated, in three groups based on the time of abstinence: up to four years (n=39), between four and eight years (n=35) and above eight years (n=42); as well as three groups based on relapses: no relapse (n=60), with one relapse (n=23), and with several relapses (n=33). Statistically significant results regarding the quality of social support have been noticed: a) By family members – those without relapses (2 items) and those with abstinence between four and eight years (2 items); b) By friends – those without relapse (1 item); c) From other significant persons – those without relapses (1 item) and those with abstinence over eight years (1 item).

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Prekybos alkoholiu vietų reguliavimas: Pirmosios ir Antrosios Lietuvos Respublikos patirtys

Prekybos alkoholiu vietų reguliavimas: Pirmosios ir Antrosios Lietuvos Respublikos patirtys

Author(s): Ilona Tamutienė,Rita Andrejeva,Aistė Lazauskienė / Language(s): Lithuanian Issue: 1/2016

In 1928-1931, annual consumption of legal pure alcohol per capita was just 1.17 litres, while in 2014 the alcohol consumption per capita was 12.7 litres. The alcohol outlet density is one of the most significant factors for the indicators of alcohol consumption. The aim of this paper is to compare the characteristics of the regulation of retail alcohol outlets in the First (1918-1940) and Second (1990-2015) Republic of Lithuania. The goals are the following: to evaluate the aspects of alcohol outlet density, expiration dates and issue conditions of seller licences, and the maintenance of public order of seller licence usage as well as assurance of safety in the neighbourhoods, and to determine the period of Seimas (governing parties) ruling during which fundamental changes occurred in the liberalization or prohibition with regards to regulation of alcohol outlets. The paper is based on the method of document analysis. It was determined that the regulation of alcohol outlets was much stricter in the period of the First Republic of Lithuania than in the period of the Second Republic. In the First Republic of Lithuania, the regulation of the density of alcohol outlets was connected to the assurance of public safety and prevention of noise, the community was involved in the regulation of the density of alcohol outlets, the density of alcohol outlets was regulated, the prohibited distances were defined between alcohol outlets and places of worship, cemeteries, healthcare and education establishments or other institutions significant to the public, the issued licences were short-term, for the period of one year. Even though in the period of the ruling of Antanas Smetona in 1934 the alcohol outlet regulation was liberalized, eliminating the influence of residents and municipalities on the issuing of licences, alcohol outlet regulation still remained stricter than in the period of the Second Republic of Lithuania. In 2002, the social-democratic coalition, which had the majority in the government, strongly liberalized the alcohol outlet regulation: it abolished any regulation of alcohol outlet density, eliminated short-term licences and authorised alcohol sales in sanatoriums, kiosks and petrol stations. Only the political group of Homeland Union-Lithuanian Christian democrats, which had the majority in the Seimas of 2008-2012, managed to prohibit sales in kiosks and petrol stations, but the density remained unregulated, the licences were still short-term, the licencing was unconnected to public safety and assurance of public order, and the community’s influence was restricted only to expression of opinion on the issuing of new alcohol seller licences in the blocks of flats they reside in. It is recommended to connect alcohol outlet regulation with public safety and assurance of public order, to regulate outlet density, to issue short-term licences, and to empower the residents to participate in the alcohol outlet regulation.

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AN INVESTIGATION OF THE RELATIONSHIP BETWEEN DIGITAL GAME ADDICTION, GENDER AND REGULAR SPORT PARTICIPATION

AN INVESTIGATION OF THE RELATIONSHIP BETWEEN DIGITAL GAME ADDICTION, GENDER AND REGULAR SPORT PARTICIPATION

Author(s): Narullah Emir Ekinci,Omer Ozer,Umit Dogan Ustun / Language(s): English Issue: 2/2016

This study aims to investigate digital game addiction of high school students according to gender and regular sport participation. For this 398 high school students who were randomly chosen voluntarily participated in the study. In addition to personal information from the Turkish version of Lemmens and colleagues’a game addiction scale was used as a data gathering tool. The Turkish adaptation of the scale was done by Aylin Yalcın Irmak and Semra Erdogan in 2015. The Turkish version of the scale consists of one factor and seven items anchored with a five Likert type scale. In the evaluation of the data linear regression was used. The findings of this study revealed that there was a positive relationship between gender and digital game addiction.

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Hazard jako problem współczesnych społeczeństw.

Hazard jako problem współczesnych społeczeństw.

Author(s): Artur Michał Banaszak / Language(s): Polish Issue: 1/2014

The addictions are a major problem of the modern world. Their types are varied and various fields of science deal with them. One of the phenomena that can become an addiction is gambling. It is betting on certain events, the outcome of which is difficult to predict and depends only on the fortuity. The phenomenon of gambling in itself is not a problem, but can lead to significant problems having a devastating impact on the lives of individuals and society. The object of this research is the phenomenon of gambling considered primarily in terms of its harmfulness. The author analyzes the different situations of gambling. It will be shown how to recognize pathological gambling and what characteristics are people addicted to gambling. In addition, we will discuss gambling as a disease. The purpose of this study is to demonstrate that gambling can be harmful to people and that it is a disease that today affects more and more people.

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Strategia redukcji szkód w pracy z osobami uzależnionymi od narkotyków i alkoholu

Strategia redukcji szkód w pracy z osobami uzależnionymi od narkotyków i alkoholu

Author(s): Ewa Dubiel / Language(s): Polish Issue: 1/2016

Polityka państw europejskich, Stanów Zjednoczonych, Ameryki Południowej i Australii od kilkunastu lat zmierza w kierunku restrukturyzacji systemu pomocy osobom uzależnionym wdrażając działania, których celem jest ograniczanie szkód zdrowotnych i społecznych wynikających z używania substancji psychoaktywnych. Wiele krajów oferuje dostęp do niskoprogowych programów, czyli takich, w których udział nie nakłada na uczestnika obowiązku utrzymywania abstynencji i stosowania się do wygórowanych zasad i obowiązków placówki odwykowej. Redukcja szkód jest filozofią opartą na pragmatycznych i realistycznych celach pracy z osobami uzależnionymi i użytkownikami. Zakłada, że każda, nawet najmniejsza zmiana jest ważna i należy ją wzmacniać. Programy redukcji szkód funkcjonują zazwyczaj w kilku sektorach oddziaływań społecznych – terapii, resocjalizacji, profilaktyki zachowań ryzykownych i pomocy społecznej. W Polsce poszerzenie oferty terapeutycznej o programy redukcji szkód jest zjawiskiem nadal marginalnym, a zmiany w systemie leczenia uzależnień nie nadążają za dynamicznymi zmianami wzorca używania substancji psychoaktywnych. Monolityczny system pomocy, oparty na abstynencji, jest niewystarczający i nie odpowiada na zmieniające się potrzeby w zakresie pomocy osobom tego potrzebującym.

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ALKOHOLIZAM I ADOLESCENTI

ALKOHOLIZAM I ADOLESCENTI

Author(s): Ifeta Ličanin,Amira Redžić,Abdulah Kučukalić / Language(s): Bosnian Issue: 16/2003

Alcohol abuse is a worldwide problem that threatens social, economic, and family life. Our country is a postwar society, currently going through a transition period. Therefore, various risk factors related to alcohol and other kinds of substance abuse, like social, economic and health factors can be found here. Parental influence and peer pressure seem to have a strong impact on adolescents' behavior. Youngsters like to experiment with risky life styles, without adequate knowledge about long-term health effects. lt is well known that drug abuse is common in early adolescence, with almost the same epidemiological characteristics in both economically developed and undeveloped countries. In order to develop an appropriate prevention strategy, it is necessary to be aware of all relevant risk factors first. Objective: Finding risk factors relating to alcohol abuse among adolescents.

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Addictive effects of alcohol

Addictive effects of alcohol

Author(s): Bożena Witek,Danuta Rochon-Szmejchel,Peter Liedke / Language(s): English Issue: I/2016

Alcohol is one of legal psychoactive substances which are commonly consumed and often abused by people of all social classes. Alcohol is capable of changing the functions of individual organs and systems of the organism, as well as the structure and function of cells. Research studies have determined a significant correlation between prolonged consumption of alcohol, the generation of reactive oxygen species, and the increased risk for many disorders, including cardiovascular diseases, arterial hypertension, neoplastic diseases, or diseases of the nervous and muscular systems. The organ which is the most susceptible to its toxic effects is the liver. In acute and chronic alcohol poisoning, the excessive build-up of lipids in the liver may lead to chronic diseases of the organ, such as cirrhosis, hepatitis or hepatic steatosis. Continuous consumption of alcohol may also contribute to undernutrition and consequently a deficiency of many nutrients, including vitamins. Alcohol consumption also induces changes to the carbohydrate and lipid metabolism in skeletal muscles. Its excess may lead to such conditions as myopathy, resulting in the atrophy of skeletal muscles. Changes triggered by the chronic or excessive consumption of alcohol can be observed at the structural, physiological and molecular levels of the organism.

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Uzależnienie od nikotyny wśród studentów uczelni lubelskich

Uzależnienie od nikotyny wśród studentów uczelni lubelskich

Author(s): Beata Kropornicka,Bożena Baczewska,Paulina Domańska,Elżbieta Nowicka,Bartłomiej Drop,Jadwiga Daniluk / Language(s): Polish Issue: 3/2015

Smoking is one of the major problems in modern medicine. Poland still remains at the forefront of countries where the number of people addicted to nicotine is relatively large, and smoking is a major problem in environments of academic students. The aim of the study is to understand and compare the reasons of smoking, the degree of nicotine dependence and motivation to quit smoking of students of medical and non-medical universities. The methods employed during the study are two questionnaires; the questionnaire of Fagerström used for assessing the degree of nicotine dependence and the questionnaire of Schneider used for assessing the motivation to quit smoking. The study was carried out anonymously from April to June 2013 and involved 200 students from Lublin University of Technology and the Medical University of Lublin. During the study signi icant differences between students of medical and non-medical universities in terms of initiation and duration of nicotine addiction have been shown. The most common cause of reaching for cigarettes by respondents from both universities is stress and the situation in which students smoke cigarettes most commonly is during social meetings. Respondents from non-medical universities often reach for a cigarette out of boredom or to make contacts. They are in a higher degree of dependence on nicotine, experience greater satisfaction from smoking and, at the same time, their habit is gaining greater acceptance on the part of their friends. Students of medical schools are more aware that addiction to nicotine has a negative impact on health and are more motivated to quit smoking than their peers. Sociodemographic factors such as gender, place of residence, the economic situation did not affect the level of motivation to quit smoking by respondents from both types of schools. By contrast, the degree of nicotine dependence of students from medical schools is impacted only by their economic situation.

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Satysfakcja z życia w grupie osób uzależnionych od alkoholu i narkotyków. rola zasobów osobowościowych i zachowań zdrowotnych.

Satysfakcja z życia w grupie osób uzależnionych od alkoholu i narkotyków. rola zasobów osobowościowych i zachowań zdrowotnych.

Author(s): Karol Konaszewski,Jolanta Muszyńska / Language(s): Polish Issue: 2/2019

Artykuł prezentuje wyniki badań, których celem było ustalenie roli zasobów osobowościowych i zachowań zdrowotnych jako czynników warunkujących satysfakcję z życia w grupie osób uzależnionych od alkoholu i narkotyków. W artykule prezentujemy całościowy model predyktorów uwzględniający prężność, wspólnotowość sprawczość, zachowania zdrowotne i satysfakcję z życia. Jego dopasowanie było testowane poprzez analizę wielu zmiennych, które dotychczas były badane oddzielnie: prężność wspólnotowość, sprawczość i zachowania zdrowotne jako zmienne wyjaśniające oraz satysfakcja z życia jako zmienna wyjaśniana. Założyliśmy, że orientacja sprawcza i wspólnotowa, prężność i zachowania zdrowotne jako zasoby osobiste można uznać za czynniki wpływające na kształtowanie satysfakcji życiowej a w konsekwencji na przebieg terapii uzależnień. Z naszych badań wynika, że zasoby osobiste są czynnikami determinującym satysfakcję życiową co może przyczyniać się w znacznej mierze do walki z chorobą w tym z uzależnieniem.

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Zmiana paradygmatów w terapii uzależnień

Zmiana paradygmatów w terapii uzależnień

Author(s): Tomasz Głowik / Language(s): Polish Issue: 1/2019

Paradygmaty stanowią modelowy opis problemów i rozwiązań. Są ważne, ponieważ wynikają z nich konkretne metody pracy, pomysły na interpretację np. zachowań osób, które wymagają pomocy, kryteria sukcesu lub porażki. W ostatnich latach w lecznictwie odwykowym zaczęła się i nadal trwa istotna zmiana dotychczas obowiązujących w nim paradygmatów w obszarze rozumienia osób uzależnionych i samego zjawiska uzależnienia. Ma ona wpływ na pojawienie się nowych programów terapeutycznych, które nie są ukierunkowane jedynie na abstynencję, ale także na programy ograniczania picia oraz programy redukcji szkód. Warto jednak także podkreślić, że nie są to programy dla wszystkich, a każdy z nich jest adresowany do ściśle zdefiniowanej grupy osób z szeroko rozumianym problemem uzależnień.

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Change in paradigms in addiction therapy

Change in paradigms in addiction therapy

Author(s): Tomasz Głowik / Language(s): English Issue: 1/2019

Paradigms constitute a model description of problems and their solutions. They are important as certain methods of work, ideas for interpreting e.g. behaviour of people in need for help, criteria for success or failure come from them. Recent years have brought an important change of paradigms, which can still be seen happening in therapeutic rehabilitation in the area of understanding addicts as well as the understanding of addiction itself.The change influences the occurrences of new therapeutic programs, which are no longer focused on sobriety itself, but it also has a huge influence on alcohol abuse and harm reduction programs. It must be emphasized that these are programs that are not designed for everyone and each of them is dedicated to strictly defined group of people with an addiction in a broad sense.

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Satisfaction with life in a group of alcohol and drug addicts. The role of personal resources and health behaviors

Satisfaction with life in a group of alcohol and drug addicts. The role of personal resources and health behaviors

Author(s): Karol Konaszewski,Jolanta Muszyńska / Language(s): English Issue: 2/2019

The article presents the results of research aimed at determining the role of personality resources and health behaviors as factors determining life satisfaction among alcohol and drug addicts. In the article, we present a holistic model of predictors that takes into account resilience, communality, causality, health behaviors and life satisfaction. Its suitability has been tested through the analysis of a number of variables that have so far been examined separately: resilience, communality, causality and health behaviors as explanatory variables and satisfaction of life as a variable to be explained. We assumed that causative and communal orientation, resilience and health behaviors as personal resources can be considered as factors influencing life satisfaction and, in consequence, the course of addiction therapy. Our research reveals that personal resources are determinants of life satisfaction, which can make a significant contribution to the fight against the disease, including addiction.

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Non-substance Addictions in the Context of Individual and Social Health

Non-substance Addictions in the Context of Individual and Social Health

Author(s): Roman Adamczyk / Language(s): English Issue: 1/2019

The article deals with present-day non-substance-related (behavioral, process) addictions that interfere with the complex of individual and social health. Selected impacts of addiction onto the physical, mental and social level are discussed along with the interplay of addiction factors and health.

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Rolul familiei in consumul de droguri la tineri

Rolul familiei in consumul de droguri la tineri

Author(s): Francisc Maier / Language(s): Romanian Issue: 4/2015

The article proposes to identify, on the basis of the consultation of the specialty literature, the factors which influence the consumption of drugs amongst teenagers, as well as the sense in which their main dimensions act. The studies performed on teenagers (Rascanu R (2008) Addiction and Drugs‑theoretical and ameliorative clinic aspects, Bucharest, Publishing House Universitatii, p. 26.) highlighted amongst the internal causes of drug consumption: the curiosity, the temptation in the form of the „forbidden fruit mechanism”; the desire of high sensations; the lack of maturity/responsibility; personal problems, troubles, despair, loneliness, the lack of friends; boredom; the lack of some interesting preoccupations; emo girls /the need to stand out; and the external causes are: the ill‑fated influence of the entourage, of the „fishy” group of friends, of the unfavorable family climate, the reduced educational and cultural level; the lack of information or skewed information with regard to drugs; the imitation of film models, from newspapers or magazines. The drug consumption is tightly related to life problems, to the questions and searching of the teenagers and young. The most important social entourages are: the family, the school and the group of entourage. So the drug consumption amongst teenagers represents one of the challenges with which the humanity has to confront, its direct and indirect effects designing it as a worrying phenomenon.

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Alcohol use disorder according to DSM-5 Opportunities and constraints resulting from changing diagnostic criteria

Alcohol use disorder according to DSM-5 Opportunities and constraints resulting from changing diagnostic criteria

Author(s): Robert Modrzyński / Language(s): English Issue: 1/2020

Another revision of the DSM manual (Diagnostics and Statistical Manual of MentalDisorders – DSM-5) appeared in 2013 and introduced far-reaching changes in the understanding of psychoactive substance use disorders. The most important break through concerns the understanding of alcohol use. The move away from a dichotomous, binary understandingof alcohol dependence and abuse has allowed the creation of a new diagnostic category ofalcohol use disorder (AUD). The article addresses the issue of changes in diagnostic criteria for alcohol use disorder inthe light of the latest DSM-5 classification. The location of the category of alcohol use disorder,its definition and diagnostic criteria will be presented. The author also compares the symptoms of alcohol use disorder according to DSM-5 with the corresponding ICD-10 International Statistical Classification of Diseases and Related Health Problems) criteria. The article ends with pointing out numerous controversies concerning the new category. The challenge for future research is to plan treatment according to the severity of the alcohol disorder.

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Zaburzenie używania alkoholu według DSM-5 Możliwości i ograniczenia wynikające ze zmiany kryterów diagnostycznych

Zaburzenie używania alkoholu według DSM-5 Możliwości i ograniczenia wynikające ze zmiany kryterów diagnostycznych

Author(s): Robert Modrzyński / Language(s): Polish Issue: 1/2020

Kolejna rewizja podręcznika DSM (ang. Diagnostics and Statistical Manual of Mental Disorders – DSM-5) pojawiła się w 2013 roku i wprowadziła daleko idące zmiany w rozumieniu zaburzeń stosowania substancji psychoaktywnych. Najważniejszy przełom dotyczy rozumienia używania alkoholu. Odejście od dychotomicznego, zero-jedynkowego rozumienia uzależnienia od alkoholu i nadużywania pozwoliło na stworzenie nowej kategorii diagnostycznej zaburzeń używania alkoholu (alcohol use disorder – AUD). W artykule poruszono zagadnienie zmian w kryteriach diagnostycznych dotyczących zaburzenia używania alkoholu w świetle najnowszej klasyfikacji DSM-5. Zaprezentowano umiejscowienie kategorii zaburzeń używania alkoholu, jej definicję wraz z kryteriami diagnostycznymi.Dokonano również zestawienia objawów zaburzenia używania alkoholu wg DSM-5 z odpowiadającymi im kryteriami ICD-10 (ang. International Statistical Classification of Diseases and Related Health Problems). Na zakończenie artykułu przedstawiono liczne kontrowersje wokuł nowej kategorii. Podkreślono wyzwanie dla przyszłych badań, jakim jest planowanie leczenia w zależności od stopnia ciężkości zaburzenia używania alkoholu.

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ANALIZA (NE)ZVANIČNIH DISKURSA O UPOTREBI DROGA U SRBIJI

Author(s): Milana Ljubičić / Language(s): Serbian Issue: 1/2021

In the article, we analyse discourse on drug abuse in contemporary Serbia. The ruling official discourse on drugs can be subsumed under the definition of moral panic, in creation of which, as well in dissemination, the media play an important role. Media uses specific vocabulary to send message warning of an impending social catastrophe. This tactic is effective: recipients of media content become anxious and frightened by the downfall of the society that awaits them in the near future. So logically they are converting into supporters of official discourses on the topic. In the end, this process has the power to briefly connect a shredded tissue of social cohesion, but also to produce a lack of freedom of citizens. In order to investigate whether drug-related moral panics in our country can have such implications, in this paper we analyzed the official discourse embodied in anti-drug policies, and the public discourse offered by media. Findings suggest that policymakers are calling on war against drugs, and name prevention and criminalization as the most successful strategies to fight it. The recipients of media content are agreeing with them. Furthermore, there is no doubt that such o discourse encourages the spread of moral panic about drugs, as well as social cohesion. Although abstractly defined, the enemy – drug, has the power to unite. However, it also causes a lack of freedom. Because of the narrative of the impending catastrophe, the citizens feel powerless and therefore demand from the higher state authorities to act in the name of the social future.

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Sociology of Alcohol Consumption – In Search of a Theory

Sociology of Alcohol Consumption – In Search of a Theory

Author(s): Erik Brezovec / Language(s): English Issue: 2/2022

Alcohol consumption takes place in society and because of society. The “social” aspect of this phenomenon gives a meaning that manifests itself in the framework of interaction. This paper discusses basic problems of previous sociological approaches to alcohol consumption: (1) focus on a problem-oriented approach – drinking and alcoholism, (2) abstract empiricism of alcohol consumption, and (3) unclear theoretical background for a sociological approach to alcohol consumption. Focusing exclusively on alcoholism or excessive drinking neglects a number of social dimensions inherent in alcohol consumption. Therefore, when considering this phenomenon in sociological terms, clear theoretical-methodological starting points should be established in order to understand the social consumption of alcohol. The main objective of this paper was to provide a basic paradigmatic and epistemological framework for the development of a sociology of alcohol consumption. The paper starts from the assumption that two theoreticalmethodological principles should be considered: methodological individualism and methodological situationism. Each of these approaches has certain advantages and disadvantages, but in further conceptualising the paradigmatic foundations of the sociology of alcohol consumption, the paper proposed a two-level approach, that is, a synthesis of methodological situationism and methodological individualism. However, this synthesis does not constitute a theory of the sociology of alcohol consumption, but a framework for a sociological approach to the phenomenon, as well as the possibility of overcoming the problems presented in the sociological analysis of this topic.

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DZIAŁANIA POLICJI W KONTEKŚCIE ZWALCZANIA PRZESTĘPCZOŚCI NARKOTYKOWEJ WŚRÓD MŁODZIEŻY

DZIAŁANIA POLICJI W KONTEKŚCIE ZWALCZANIA PRZESTĘPCZOŚCI NARKOTYKOWEJ WŚRÓD MŁODZIEŻY

Author(s): Piotr Magdziarz / Language(s): Polish Issue: 1/2022

The aim of the study is to show the role of drugs as a factor underlying the emergence of so-cial pathology among adolescents, which is drug addiction. Initially, the genesis of the con-cept of social pathology was presented based on the literature on the subject. Then, the types of psychoactive substances were characterized, their effects on the mental and physical spheres, and their place in the life of contemporary youth. In the work, as part of the research method, mainly problem and comparative analysis was used in the field of subject literature and thematic monographs.In the modern world, drugs are recognized as one of the most serious social threats. In addition to being the root of many pathologies, they are also a profitable business for many organized crime groups. There are many reasons why people turn to psychoactive drugs. The reasons range from a desire to reduce stress, to encouragement from peers and those closest to them. These types of chemical compounds have been with man since the creation of the primitive community and were originally used as a means for the individual to connect with god, due to their psychedelic and intoxicating effects on the central nervous system. The real problem of social as well as criminal nature started when both drug dealers and consumers became younger and younger people. Psychoactive drugs for young people are available practically in all places where they hang out. These are restaurants, pubs, discos, the nearest neighbourhood, and even school. Another major problem is the change in drug use preferences of young people. In the past, marijuana and hashish, which are considered to be light drugs, were popular. Currently, amphetamines and the more expensive cocaine are similarly popular. As time goes by, drugs become more than just an integral part of weekend fun for young people. As they grow and take on new social roles, psychoactive drugs prove indispensable at school and then at work.

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Spektroskopická charakterizace peptidů a polypeptidů pro podporu růstu svalové hmoty

Spektroskopická charakterizace peptidů a polypeptidů pro podporu růstu svalové hmoty

Author(s): František Králík,Anna Kvíčalová,Martin Kuchař,Vladimír Setnička / Language(s): Czech Issue: 2/2023

Ghrelin is a hormone enhancing the drive to eat and is sometimes called a “hunger hormone”. In human organism, it binds to the receptor GHS-R1a, which leads to the release of the growth hormone. Growth hormone secretagogues (GHSs) are a group of compounds that interact with GHS-R1a receptor in a similar way to ghrelin and thus enhance rapid muscle growth. Although GHSs are listed in the World Anti-Doping Agency’s Prohibited List, they have been abused by professional and amateur sportsmen and bodybuilders. The current situation demands development of reliable analytical methods for clear and rapid identification of these substances. In this work, the electronic circular dichroism spectroscopy is presented as an innovative, fast and reliable method for the analysis of GHSs group peptides.

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