Procreative Selection to Help Others: Saviour Siblings
Procreative Selection to Help Others: Saviour Siblings

Author(s): Ketrien Devolder
Subject(s): Politics / Political Sciences, Philosophy, Social Sciences
Published by: Institut za filozofiju i društvenu teoriju
Keywords: saviour siblings; preimplantation genetic diagnosis (PGD); HLA tissue typing; stem cell transplantation; procreative selection; reproductive ethics
Summary/Abstract: Preimplantation tissue typing has been used to enable families to create so called 'saviour siblings'; tissue matched children that can serve as a stem cell donor for a sick sibling in need of an allogeneic haematopoietic stem cell transplantation. Haematopoietic stem cells are blood forming stem cells residing in the bone marrow, the peripheral blood, and the umbilical cord blood. For several lethal malignant and some non-malignant disorders, haematopoietic stem cell transplantation is currently the only therapeutic approach (Benito et al. 2004).

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