Prophylactic effect of lactobacilli and bifidobacteria probiotic strains on experimental bacterial vaginitis Cover Image

Prophylactic effect of lactobacilli and bifidobacteria probiotic strains on experimental bacterial vaginitis
Prophylactic effect of lactobacilli and bifidobacteria probiotic strains on experimental bacterial vaginitis

Author(s): L. P. Babenko, L.M. Lazarenko, R.V. Bubnov, M.J. Spivak
Subject(s): Evaluation research
Published by: Дніпропетровський національний університет імені Олеся Гончара
Keywords: Lactobacillus; Bifidobacterium; Staphylococcus; microbiota; vagina; gut; mice;

Summary/Abstract: The objective of the study was determining the prophylactic effect of Lactobacillus casei IMV B-7280, L. acidophilus IMV B- 7279, L. delbrueckii subsp. bulgaricus IMV B-7281, Bifidobacterium animalis VKL and B. animalis VKB probiotic strains on experimental vaginitis in BALB/c mice induced by Staphylococcus aureus 8325-4. The infection with S. aureus 8325-4 caused an imbalance of microbiota in the vagina and intestine, as evidenced by an increase in the number of opportunistic microorganisms and a decrease in the amount of lactobacilli and bifidobacteria. L. casei IMV B-7280, B. animalis VKL and B. animalis VKB probiotic strains altered the microbiota spectrum of the vagina and intestine of Staphylococcus-infected mice: the amount of Lactobacillus and bifidobacteria increased with the reduction of the number of opportunistic microorganisms.

  • Issue Year: 27/2019
  • Issue No: 2
  • Page Range: 170-176
  • Page Count: 7
  • Language: English