NEUROTRANSPLANTATION EMBRYONAL TISSUE IN PARKINSONISM AND HUNTINGTON’S CHOREA IN SLOVAK REPUBLIK
NEUROTRANSPLANTATION EMBRYONAL TISSUE IN PARKINSONISM AND HUNTINGTON’S CHOREA IN SLOVAK REPUBLIK

Summary/Abstract: This article is dedicated the memory on 30th anniversary of first neurotransplantations in Slovakia in patients with Parkinsonism and Hungtington’s chorea. 12th. July 1989 in Slovakia (formerly Czechoslovakia) was first neurotransplantation embryonal brain tissue implanted in the patients with Parkinsonisms on the Neurosurgical clinic, Faculty of Medicine Comenius University in Bratislava, Slovakia. After 10 neurotransplantations of embryonal brain tissue were interrupted by Ministry of Healthy Slovak republic. Method: Embryonal brain tissue was implanted into the nucleus caudate, using stereotaxy assisted by CT. A cannula enables to place into to brain 3 or 4 tissue samples on the determined trajectory without repetition, implanted successively applied into 4 or 5 loci caudate nucleus in Parkinsonism and in both caudate nucleus in Huntington’s chorea. Results: Six patients resistant on medication or with toxic side effect of drugs with Parkinsonism were transplanted. Postoperatively patients were hospitalised and observed findings were compared with preoperative status. Transplantation influences mainly on rigidity and akinesia, less on tremor.

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