Вплив структури ліганду на протипухлинні та антиоксидантні властивості кластерних сполук ренію
Influence of ligand structure on anticancer and antioxidant properties of rhenium cluster compounds
Author(s): I. V. Leus, E. D. Skorik, N. V. Beztsinna, N. I. ShtemenkoSubject(s): Sociobiology
Published by: Дніпропетровський національний університет імені Олеся Гончара
Keywords: ligand; anticancer and antioxidant properties; rhenium cluster compounds;
Summary/Abstract: Under the model growth of T8 Guerin’s carcinoma in rats we studied the anticancer activity of the system rhenium-platinum, which includes cis-dicarboxylates of rhenium (III) with different alkyl ligands, erythrocytes number and its morphological structure, erythrocytic stability, blood haemoglobin concentration, catalase activity and concentration of TBA-active products in the rats blood plasma. The renium-platinum system had considerable antioxidat effect and prevented the growth of tumour, that was maximal for a compound with the pivalate ligand.
Journal: Biosystems Diversity
- Issue Year: 17/2009
- Issue No: 3
- Page Range: 46-53
- Page Count: 8
- Language: Ukrainian