АКТИВНИ И НОВОДИЈАГНОСТИЦИРАНИ СЛУЧАИ СО КАРЦИНОМ НА МОЧЕН МЕУР ЗА 2025 ГОДИНА ВО СТРУМИЦА, Р.СЕВЕРНА МАКЕДОНИЈА
ACTIVE AND NEWLY DIAGNOSED CASES OF BLADDER CANCER FOR 2025 IN STRUMICA, REPUBLIC OF NORTH MACEDONIA

Summary/Abstract: Bladder cancer is a significant public health problem with a growing incidence worldwide. According to data from the World Health Organization and the International Agency for Research on Cancer, it is among the most common malignant neoplasms of the urinary tract and is among the top ten most common cancers in the world. The disease is characterized by a high recurrence rate, especially in non-muscle-invasive forms, which requires long-term and regular cystoscopic monitoring. Despite the relatively good prognosis in the early stages, bladder cancer is a disease with significant morbidity, the need for repeated interventions and high health costs. The most significant risk factor for the development of bladder cancer is cigarette smoking, which is metabolized and eliminated in the urine and comes into direct contact with the urothelium. Other risk factors include occupational exposure to aromatic amines (in the chemical, textile and leather industries), chronic inflammatory conditions of the bladder, long-term catheterization, previous radiotherapy in the pelvic region, as well as the use of certain cytostatic drugs. Objective: The aim of this study is to analyze active cases of bladder cancer during 2025, with special attention to newly diagnosed patients, their demographic characteristics and clinical presentation. Materials and methods: This study presents a retrospective descriptive analysis of patients with bladder cancer followed during 2025 in the Urology Outpatient Department of the Public Health Institution "General Hospital" Strumica. The obtained data are systematized, presented graphically. Results: This study included 98 patients: 26 newly diagnosed in 2025 and 72 patients diagnosed in previous years and actively under control. Males dominate with 73 patients (74.5%). Females are less numerous with 25 patients (25.5%). The average age is 67 years. The most common group is 61-70 years (48.0%). The youngest patient is a 47-year-old woman, and the oldest patient is also a woman, 81 years old. Recurrence was observed in 34 patients or 34.6% of whom: men - 25 (34.2%) women - 9 (36%). 83 patients (84.7%) are smokers while 15 patients (15.3%) are non-smokers. A positive family history is present in 6 patients (6.1%) while 92 patients provided information about a negative family history. Conclusion: The analysis of active and newly diagnosed cases allows for better planning of healthcare resources, improvement of diagnostic and therapeutic protocols, as well as improved patient monitoring.

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