OPPORTUNISTIC INFECTIONS IN HIV POSITIVE PATIENTS – A SINGLE CENTER EXPERIENCE
OPPORTUNISTIC INFECTIONS IN HIV POSITIVE PATIENTS – A SINGLE CENTER EXPERIENCE

Summary/Abstract: (acquired immune deficiency syndrome) is a late presentation of an infection with HIV. It is characterized by a clinical picture of various opportunistic infections and a decreasing number of CD4+ T lymphocytes. Opportunistic infections are diseases caused by microorganisms, which significantly more often affect immunocompromised people. GOAL Describe the clinical and laboratory characteristics of HIV- positive individuals with one or more opportunistic infections. To examine the frequency and prevalence of the most common opportunistic infections in patients with HIV infection who are on HAART and who are older than 45 years, compared to those who are younger than 45 years. A retrospective, comparative, clinical study was conducted that included hospitalized HIV-positive patients in the period from 1/1/2018 to 31/12/2022 at the Clinic for Infectious Diseases of the Clinical Center of the University of Sarajevo, Bosnia and Herzegovina. Out of a total of 50 patients in the sample, there were 42 men (84%) and 8 women (16%). 58% of patients were under 45 years of age, and 42% were over 45 years of age. The most prevalent infection was candidiasis 32%. A significant difference in the number of people with toxoplasmosis over the age of 45 with more cases, compared to the group of patients under the age of 45, was proven. No significant difference was found in the prevalence of tuberculosis and Pneumocystis pneumoniae infection between the two age groups of patients. Continuous control examinations allow easier and faster identification of opportunistic infections, even before the infection gives changed clinical parameters.

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