EFFECT OF GLUTEN-FREE, CASEIN-FREE DIET, SUPPLEMENTS AND DIGESTIVE ENZYMES ON GASTROINTESTINAL SYMPTOMS AND BEHAVIOR IN INDIVIDUALS WITH AUTISM SPECTRUM DISORDER
EFFECT OF GLUTEN-FREE, CASEIN-FREE DIET, SUPPLEMENTS AND DIGESTIVE ENZYMES ON GASTROINTESTINAL SYMPTOMS AND BEHAVIOR IN INDIVIDUALS WITH AUTISM SPECTRUM DISORDER

Summary/Abstract: Autism Spectrum Disorder (ASD) presents as a complex neurodevelopmental condition, encompassing various symptoms, including gastrointestinal (GI) issues. This study explores the impact of a gluten-free, casein-free diet (GF/CFD), complemented by digestive enzymes and nutritional supplements, on GI symptoms and behavior in individuals diagnosed with ASD. The study includes 70 participants, with 34 in the treated group and 36 in the non-treated group, spanning a 6-month duration. The investigation evaluates changes in GI symptoms, behavioral measures, and co-occurring psychopathological conditions. Results reveal significant improvements in numerous GI symptoms, such as abdominal discomfort, bloating, constipation, hard stool, rumbling, and flatus, among others, following the dietary intervention. Notably, these positive changes persist and deepen over time. Additionally, certain behavioral aspects, including play skills, sociability, eye contact, sleep, stools/gut issues, display substantial enhancements in the treated group compared to the non-treated group. Language and cognition/thinking exhibit not significant improvements. The total score of the treatment group substantially surpasses that of the non-treatment group. This study underscores the importance of nutritional interventions in managing ASD, shedding light on the potential benefits of a GF/CFD coupled with supplements and digestive enzymes. The findings emphasize the need for a holistic treatment approach that includes nutritional therapy in addressing the multifaceted challenges presented by ASD, particularly in individuals with co-occurring GI symptoms. Further research in this domain is encouraged, as it may open new therapeutic avenues and improve the quality of life for individuals affected by this prevalent developmental disorder.

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