ПОДАВЛЕНИЕ СТРАХА: УЧАСТИЕ ГАМКЕРГИЧЕСКОЙ НЕЙРОМЕДИАТОРНОЙ СИСТЕМЫ
RESTRAIN OF FEAR: PARTICIPATION OF GABA NEUROTRANSMITTER SYSTEM
Author(s): Galina I. Shulgina, Darya A. Berezhnaya, Nikolai A. ParfentyevSubject(s): Social Sciences, Psychology
Published by: Scientia Socialis, UAB
Keywords: training; freezing; fear; inhibition; disinhibition; GABA; Phenibut;
Summary/Abstract: In experiences on rats in the conditions of free behavior at development of a conditioned of passive avoidanсe reflex (the first series) and a defensive reflex and a conditional inhibition (the second series) it is revealed, and elaboration of internal inhibition and Phenibut – a nonspecific agonist of GAMKA and GAMKB receptors cause in experimental animals weakening of freezing arising in a dangerous situation, and a disinhibition of research behavior. Results of experiences in the accounting of data of the literature allow to assume that both factors, and elaboration of internal inhibition, and Phenibut weaken freezing – the phenomenon used in experiments as a biological analog of fear, owing to increase of level of activity of the GABA neurotransmitter system of a brain.
Journal: Problems of Psychology in the 21st Century
- Issue Year: 6/2013
- Issue No: 1
- Page Range: 71-85
- Page Count: 15
- Language: Russian