THE IMPORTANCE OF IMMUNOFLUOROMETRIC METHOD (DELFIA) IN EARLY DIAGNOSTICS AND SCREENING OF CONGENITAL HYPOTHYROIDISM Cover Image

THE IMPORTANCE OF IMMUNOFLUOROMETRIC METHOD (DELFIA) IN EARLY DIAGNOSTICS AND SCREENING OF CONGENITAL HYPOTHYROIDISM
THE IMPORTANCE OF IMMUNOFLUOROMETRIC METHOD (DELFIA) IN EARLY DIAGNOSTICS AND SCREENING OF CONGENITAL HYPOTHYROIDISM

Author(s): Albena Nikolova, Velice Nikolova
Subject(s): Social Sciences
Published by: Scientific Institute of Management and Knowledge
Keywords: thyroid gland; congenital hypothyroidism; immunofluorometric methods; DELFIA method

Summary/Abstract: Congenital hypothyroidism is inadequate thyroid hormone production in newborn infants. It can occur because of an anatomic defect in the gland, an inborn error of thyroid metabolism, or iodine deficiency. Thisis the most common neonatal endocrine disorder, and historically, thyroid dysgenesis was thought to account for approximately 80% of cases.The aim of this article is to emphasize the importance of the DELFIA method as a common molecular biological methods in early diagnostics and screening of neonatal congenital hypothyroidismand further treatment. The research uses a descriptive approach that includes detail comparation and review of results about congenital hypothyroidism during today, also this article include and evalueted results based on the research from the Public Health Institution Clinical Hospital -Stip, for theperiod from 2016 to 2018. As a conclusion of this article, based from our results from the Public Health Institution Clinical Hospital -Stipand results from other authors and clinical research in the world, with detail explanation of this immunofluorometric methodDELFIA we want to highlights the importance of this method in early laboratory diagnostics and daily routine technics and screening of congenital hypothyroidismand and further treatment.

  • Issue Year: 40/2020
  • Issue No: 4
  • Page Range: 673 - 679
  • Page Count: 7
  • Language: English